你指挥一队小虫子在手绘的2D战场上轮流开火，用八十多种武器和工具把对手炸飞出地图，还要利用地形挖隧道、设陷阱、抢占有利位置。和朋友一起玩时，可以本地或在线对战，最多五名对手互相结盟又互相背叛，一发火箭弹把自己轰进海里也是常事，最后站着的虫子才算赢。
Worms W.M.D 是一款 2D 横版回合制炮火射击游戏。你指挥一支虫虫小队，在手绘风格的战场上与对手轮流行动。每一回合都要考虑角度、力度和地形，把敌人炸出场外，让自己活到最后。地图可以被炸出大洞，隧道、掩体和高低差都是可以利用的资源。行动顺序和资源分配需要提前想好，一发打偏可能就把优势让出去。
游戏支持在线对战、本地对战和排名赛，最多可与五名对手同场较量。你可以和朋友结盟再反目，也可以各自为战。除了对战，还有训练任务、战役和挑战可以单独完成，战役包含 30 个关卡，武器与工具超过 80 种。远程同乐功能让你能和朋友共享画面一起玩。
武器库里有 Holy Hand Grenade、Super Sheep、Concrete Donkey 这类经典装备，也有火箭筒等常规火力。地形既是掩护也是陷阱，把对手脚下的地面炸掉往往比直接命中更有效。游戏带有 Gore 标签，画面中会有血腥表现。回合制节奏意味着每一步都要花时间思考，适合喜欢策略规划又想看搞笑场面的玩家。
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